Mesosilver
Frank Key sells a particle-based silver product called Mesosilver. This is supposed to be a proprietary process, but it is probably made with a method invented over a century ago by Georg Bredig (1868-1944), who was the first to use electrical discharge between electrodes as a means of making colloidal gold and platinum. The 1911 edition of Encyclopedia Britannica describes it:
"Bredig's process consists in passing an electric arc between silver electrodes under water, when a brown solution is obtained."
http://www.1911encyclopedia.org/Silver
Frank claims the most important parameter is the surface area of the particles. It is true that surface area is often an important parameter. For example, many types of dust, such as flour, coal, and aluminum and iron powders, etc., can cause an explosion if suspended in the air and ignited. But the same amount sitting in a jar may burn slowly or not at all.
The importance of this is if a reaction will occur, dividing the particles to increase the surface area will increase the rate of the reaction. But if the reaction won't occur, the surface area is irrelevant. For example, most rocks won't burn even when pulverized to make sand. Sand won't burn, even if it is ground into a fine powder.
The problem with Frank's claims is the silver particles have little or no biological activity. The silver needs to be dissolved in the form of ions in order to be used by the body or have any effect on pathogens. It should also be noted that silver has the smallest possible size when it is in the form of ions. This invalidates Frank's arguments when he claims the inert particles he produces are the most effective. In fact, many people have reported taking his product and found it doesn't work.
There is a small amount of silver ions in Mesosilver, approximately 3ppm. But this is far below the desired level of 16 to 20 ppm that is needed to obtain the best results.
Frank has some useful information on silver, with an obvious bias towards particles. Most of the general information is quite accurate, but there are frequent errors and omissions you have to watch out for.
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Definition of Terms
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Commercial Product Reports (Scroll down to "Percent of Metal Content Table")
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TEM Images of Ionic Silver Solutions Describes the problems associated with attempting to use a Transmission Electron Microscope (TEM) to examine the particles in ionic silver solutions. Why the images produced by a TEM are deceptive and misleading is explained. These images are often used to market ionic silver products.